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Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report

BACKGROUND: ST elevation myocardial infarction is defined as acute myocardial injury with necrosis due to myocardial ischemia. The frequent cause is thrombotic occlusion of atherosclerotic coronary arteries. In particular situations, thromboembolism can cause myocardial infarction in patients with n...

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Detalles Bibliográficos
Autores principales: Bengel, Christopher Paul, Müller-Gastell, Denisa, Al-Najjar, Bassam, Cherednichenko, Irina, Kacapor, Rifat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185944/
https://www.ncbi.nlm.nih.gov/pubmed/37193962
http://dx.doi.org/10.1186/s12872-023-03284-x
Descripción
Sumario:BACKGROUND: ST elevation myocardial infarction is defined as acute myocardial injury with necrosis due to myocardial ischemia. The frequent cause is thrombotic occlusion of atherosclerotic coronary arteries. In particular situations, thromboembolism can cause myocardial infarction in patients with normal coronary arteries. CASE PRESENTATION: We report a particular case of myocardial infarction in a young, previously healthy patient with non-atherosclerotic coronary arteries and inflammatory bowel disease. Although we performed an extensive work up, no clear pathophysiological cause could be diagnosed. Most likely, myocardial infarction was associated with a hypercoagulative state related to systemic inflammation. CONCLUSION: The mechanisms of coagulation disturbances in the context of acute and chronic inflammation are not yet fully understood. A better understanding of cardiovascular events in patients with inflammatory bowel disease might lead to new treatment approaches of cardiovascular disease. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-023-03284-x.