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Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report

BACKGROUND: ST elevation myocardial infarction is defined as acute myocardial injury with necrosis due to myocardial ischemia. The frequent cause is thrombotic occlusion of atherosclerotic coronary arteries. In particular situations, thromboembolism can cause myocardial infarction in patients with n...

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Autores principales: Bengel, Christopher Paul, Müller-Gastell, Denisa, Al-Najjar, Bassam, Cherednichenko, Irina, Kacapor, Rifat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185944/
https://www.ncbi.nlm.nih.gov/pubmed/37193962
http://dx.doi.org/10.1186/s12872-023-03284-x
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author Bengel, Christopher Paul
Müller-Gastell, Denisa
Al-Najjar, Bassam
Cherednichenko, Irina
Kacapor, Rifat
author_facet Bengel, Christopher Paul
Müller-Gastell, Denisa
Al-Najjar, Bassam
Cherednichenko, Irina
Kacapor, Rifat
author_sort Bengel, Christopher Paul
collection PubMed
description BACKGROUND: ST elevation myocardial infarction is defined as acute myocardial injury with necrosis due to myocardial ischemia. The frequent cause is thrombotic occlusion of atherosclerotic coronary arteries. In particular situations, thromboembolism can cause myocardial infarction in patients with normal coronary arteries. CASE PRESENTATION: We report a particular case of myocardial infarction in a young, previously healthy patient with non-atherosclerotic coronary arteries and inflammatory bowel disease. Although we performed an extensive work up, no clear pathophysiological cause could be diagnosed. Most likely, myocardial infarction was associated with a hypercoagulative state related to systemic inflammation. CONCLUSION: The mechanisms of coagulation disturbances in the context of acute and chronic inflammation are not yet fully understood. A better understanding of cardiovascular events in patients with inflammatory bowel disease might lead to new treatment approaches of cardiovascular disease. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-023-03284-x.
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spelling pubmed-101859442023-05-17 Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report Bengel, Christopher Paul Müller-Gastell, Denisa Al-Najjar, Bassam Cherednichenko, Irina Kacapor, Rifat BMC Cardiovasc Disord Case Report BACKGROUND: ST elevation myocardial infarction is defined as acute myocardial injury with necrosis due to myocardial ischemia. The frequent cause is thrombotic occlusion of atherosclerotic coronary arteries. In particular situations, thromboembolism can cause myocardial infarction in patients with normal coronary arteries. CASE PRESENTATION: We report a particular case of myocardial infarction in a young, previously healthy patient with non-atherosclerotic coronary arteries and inflammatory bowel disease. Although we performed an extensive work up, no clear pathophysiological cause could be diagnosed. Most likely, myocardial infarction was associated with a hypercoagulative state related to systemic inflammation. CONCLUSION: The mechanisms of coagulation disturbances in the context of acute and chronic inflammation are not yet fully understood. A better understanding of cardiovascular events in patients with inflammatory bowel disease might lead to new treatment approaches of cardiovascular disease. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-023-03284-x. BioMed Central 2023-05-16 /pmc/articles/PMC10185944/ /pubmed/37193962 http://dx.doi.org/10.1186/s12872-023-03284-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Bengel, Christopher Paul
Müller-Gastell, Denisa
Al-Najjar, Bassam
Cherednichenko, Irina
Kacapor, Rifat
Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
title Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
title_full Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
title_fullStr Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
title_full_unstemmed Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
title_short Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
title_sort myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185944/
https://www.ncbi.nlm.nih.gov/pubmed/37193962
http://dx.doi.org/10.1186/s12872-023-03284-x
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