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小细胞肺癌的分子分型及其治疗策略的研究进展
Small cell lung cancer (SCLC) is a malignant tumor with remarkable proliferative and invasive ability, which has very poor clinical prognosis due to lack of effective treatments. In recent years, researches on cells, animal models and tumor samples have promoted the identification of molecular subty...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial board of Chinese Journal of Lung Cancer
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186260/ https://www.ncbi.nlm.nih.gov/pubmed/37183645 http://dx.doi.org/10.3779/j.issn.1009-3419.2023.106.08 |
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author | Yang, WU Jing, ZHAO Mengzhao, WANG |
author_facet | Yang, WU Jing, ZHAO Mengzhao, WANG |
author_sort | Yang, WU |
collection | PubMed |
description | Small cell lung cancer (SCLC) is a malignant tumor with remarkable proliferative and invasive ability, which has very poor clinical prognosis due to lack of effective treatments. In recent years, researches on cells, animal models and tumor samples have promoted the identification of molecular subtypes of SCLC, discovered unique biological and clinical characteristics, and proposed potential specific therapeutic targets for different subtypes. This will encourage the development of more accurate therapeutic strategies towards SCLC, with a view to improving the prognosis of the patients. This article will review the current SCLC molecular subtypes, focus on the clinical characteristics and therapeutic strategies of different SCLC subtypes, and propose reasonable suggestions for the future treatment of SCLC. |
format | Online Article Text |
id | pubmed-10186260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Editorial board of Chinese Journal of Lung Cancer |
record_format | MEDLINE/PubMed |
spelling | pubmed-101862602023-05-17 小细胞肺癌的分子分型及其治疗策略的研究进展 Yang, WU Jing, ZHAO Mengzhao, WANG Zhongguo Fei Ai Za Zhi Review Small cell lung cancer (SCLC) is a malignant tumor with remarkable proliferative and invasive ability, which has very poor clinical prognosis due to lack of effective treatments. In recent years, researches on cells, animal models and tumor samples have promoted the identification of molecular subtypes of SCLC, discovered unique biological and clinical characteristics, and proposed potential specific therapeutic targets for different subtypes. This will encourage the development of more accurate therapeutic strategies towards SCLC, with a view to improving the prognosis of the patients. This article will review the current SCLC molecular subtypes, focus on the clinical characteristics and therapeutic strategies of different SCLC subtypes, and propose reasonable suggestions for the future treatment of SCLC. Editorial board of Chinese Journal of Lung Cancer 2023-04-20 /pmc/articles/PMC10186260/ /pubmed/37183645 http://dx.doi.org/10.3779/j.issn.1009-3419.2023.106.08 Text en https://creativecommons.org/licenses/by/3.0/This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/. |
spellingShingle | Review Yang, WU Jing, ZHAO Mengzhao, WANG 小细胞肺癌的分子分型及其治疗策略的研究进展 |
title | 小细胞肺癌的分子分型及其治疗策略的研究进展 |
title_full | 小细胞肺癌的分子分型及其治疗策略的研究进展 |
title_fullStr | 小细胞肺癌的分子分型及其治疗策略的研究进展 |
title_full_unstemmed | 小细胞肺癌的分子分型及其治疗策略的研究进展 |
title_short | 小细胞肺癌的分子分型及其治疗策略的研究进展 |
title_sort | 小细胞肺癌的分子分型及其治疗策略的研究进展 |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186260/ https://www.ncbi.nlm.nih.gov/pubmed/37183645 http://dx.doi.org/10.3779/j.issn.1009-3419.2023.106.08 |
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