Cargando…
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib
BACKGROUND AND OBJECTIVE: Systemic sclerosis (SSc) is an immune-mediated rheumatic disease characterized by fibrosis and vascular lesions. Interstitial lung disease is an early complication of SSc and the main cause of death from SSc. Although baricitinib shows good efficacy in a variety of connecti...
Autores principales: | Wang, Dandan, Wei, Yimei, Xu, Lulu, Zhang, Jie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186291/ https://www.ncbi.nlm.nih.gov/pubmed/37194022 http://dx.doi.org/10.1186/s42358-023-00305-3 |
Ejemplares similares
-
Scleroderma-related interstitial lung disease
por: Suliman, Sally, et al.
Publicado: (2017) -
Baricitinib Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice by Inhibiting TGF-β1 Signaling Pathway
por: Gu, Songtao, et al.
Publicado: (2023) -
Paclitaxel Modulates TGFβ Signaling in Scleroderma Skin Grafts in Immunodeficient Mice
por: Liu, Xialin, et al.
Publicado: (2005) -
Scar wars: is TGFβ the phantom menace in scleroderma?
por: Leask, Andrew
Publicado: (2006) -
Which is the Ideal JAK Inhibitor for Alopecia Areata – Baricitinib, Tofacitinib, Ritlecitinib or Ifidancitinib - Revisiting the Immunomechanisms of the JAK Pathway
por: Sardana, Kabir, et al.
Publicado: (2023)