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Co‐conserved sequence motifs are predictive of substrate specificity in a family of monotopic phosphoglycosyl transferases

Monotopic phosphoglycosyl transferases (monoPGTs) are an expansive superfamily of enzymes that catalyze the first membrane‐committed step in the biosynthesis of bacterial glycoconjugates. MonoPGTs show a strong preference for their cognate nucleotide diphospho‐sugar (NDP‐sugar) substrates. However,...

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Detalles Bibliográficos
Autores principales: Anderson, Alyssa J., Dodge, Greg J., Allen, Karen N., Imperiali, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186338/
https://www.ncbi.nlm.nih.gov/pubmed/37096962
http://dx.doi.org/10.1002/pro.4646

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