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Enantioselective Synthesis of Fluorinated Indolizidinone Derivatives

[Image: see text] The enantioselective synthesis of fluorinated indolizidinone derivatives has been developed. The process involved an enantioselective intramolecular aza-Michael reaction of conjugated amides bearing a pendant α,β-unsaturated ketone moiety, catalyzed by the (S)-TRIP-derived phosphor...

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Detalles Bibliográficos
Autores principales:	Escolano, Marcos, Gaviña, Daniel, Díaz-Oltra, Santiago, Sánchez-Roselló, María, del Pozo, Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186376/ https://www.ncbi.nlm.nih.gov/pubmed/37125898 http://dx.doi.org/10.1021/acs.orglett.3c00903

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