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Pharmacokinetics and Tissue Distribution of Nasal Spray of a Novel Muscarinic Receptor Blocker, 101BHG-D01, in Dogs and Rats

BACKGROUND: 101BHG-D01 is a novel selective anti-muscarinic (M) 3 receptor-blocking drug. 101BHG-D01 nasal spray is intended to be used to relieve sneezing and runny nose symptoms caused by allergic rhinitis. METHODS: In this study, we examined the plasma pharmacokinetics, tissue distribution, and m...

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Detalles Bibliográficos
Autores principales:	Wei, Hao, Wu, Lei, Jia, Yongliang, Shen, Jian, Li, Yanyou, Sun, Peng, Xie, Qiangmin, Chen, Xiaoping, Xie, Yicheng, Wang, Yingshuo, Zhao, Ziming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2022
Materias:	Drug Design and Discovery, Drug Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186379/ https://www.ncbi.nlm.nih.gov/pubmed/36464876 http://dx.doi.org/10.2174/1389200224666221201123254

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