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High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand

BACKGROUND: Despite numerous echocardiographic screening studies of children in high incidence acute rheumatic fever (ARF)/rheumatic heart disease (RHD) communities, little is known about the prevalence of RHD in adults in these populations. We sought to determine the prevalence of RHD in an urban a...

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Autores principales: Webb, Rachel, Culliford-Semmens, Nicola, ChanMow, Andrew, Doughty, Robert, Tilton, Elizabeth, Peat, Briar, Stirling, John, Gentles, Thomas L, Wilson, Nigel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186474/
https://www.ncbi.nlm.nih.gov/pubmed/37121603
http://dx.doi.org/10.1136/openhrt-2023-002253
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author Webb, Rachel
Culliford-Semmens, Nicola
ChanMow, Andrew
Doughty, Robert
Tilton, Elizabeth
Peat, Briar
Stirling, John
Gentles, Thomas L
Wilson, Nigel J
author_facet Webb, Rachel
Culliford-Semmens, Nicola
ChanMow, Andrew
Doughty, Robert
Tilton, Elizabeth
Peat, Briar
Stirling, John
Gentles, Thomas L
Wilson, Nigel J
author_sort Webb, Rachel
collection PubMed
description BACKGROUND: Despite numerous echocardiographic screening studies of children in high incidence acute rheumatic fever (ARF)/rheumatic heart disease (RHD) communities, little is known about the prevalence of RHD in adults in these populations. We sought to determine the prevalence of RHD in an urban area of South Auckland, New Zealand, where previous studies had shown the prevalence of RHD in children to be around 2%. METHODS: A cross-sectional screening study was conducted between 2014 and 2016. Echocardiography clinics were conducted at an urban Pacific-led primary healthcare clinic in New Zealand. Eligible persons aged 16–40 years were recruited according to a stratified randomised approach. Echocardiograms were performed with a standardised image acquisition protocol and reported by cardiologists. RESULTS: There were 465 individuals who underwent echocardiograms. The overall prevalence of RHD (define and borderline) was 56 per 1000 (95% CI 36 to 78 per 1000). Definite RHD was found in 10 individuals (4 of whom were already under cardiology review at a hospital clinic) with a prevalence of 22 per 1000 (95% CI 9 to 36 per 1000). Non-rheumatic cardiac abnormalities were found in 29 individuals. CONCLUSIONS: There is a high burden of both rheumatic and non-rheumatic cardiac abnormalities in this population. Rates described in New Zealand are as high as lower-middle-income countries in Africa. Addressing knowledge gaps regarding the natural history of RHD detected by echocardiography in adults is a priority issue for the international RHD community.
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spelling pubmed-101864742023-05-17 High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand Webb, Rachel Culliford-Semmens, Nicola ChanMow, Andrew Doughty, Robert Tilton, Elizabeth Peat, Briar Stirling, John Gentles, Thomas L Wilson, Nigel J Open Heart Health Care Delivery, Economics and Global Health Care BACKGROUND: Despite numerous echocardiographic screening studies of children in high incidence acute rheumatic fever (ARF)/rheumatic heart disease (RHD) communities, little is known about the prevalence of RHD in adults in these populations. We sought to determine the prevalence of RHD in an urban area of South Auckland, New Zealand, where previous studies had shown the prevalence of RHD in children to be around 2%. METHODS: A cross-sectional screening study was conducted between 2014 and 2016. Echocardiography clinics were conducted at an urban Pacific-led primary healthcare clinic in New Zealand. Eligible persons aged 16–40 years were recruited according to a stratified randomised approach. Echocardiograms were performed with a standardised image acquisition protocol and reported by cardiologists. RESULTS: There were 465 individuals who underwent echocardiograms. The overall prevalence of RHD (define and borderline) was 56 per 1000 (95% CI 36 to 78 per 1000). Definite RHD was found in 10 individuals (4 of whom were already under cardiology review at a hospital clinic) with a prevalence of 22 per 1000 (95% CI 9 to 36 per 1000). Non-rheumatic cardiac abnormalities were found in 29 individuals. CONCLUSIONS: There is a high burden of both rheumatic and non-rheumatic cardiac abnormalities in this population. Rates described in New Zealand are as high as lower-middle-income countries in Africa. Addressing knowledge gaps regarding the natural history of RHD detected by echocardiography in adults is a priority issue for the international RHD community. BMJ Publishing Group 2023-04-27 /pmc/articles/PMC10186474/ /pubmed/37121603 http://dx.doi.org/10.1136/openhrt-2023-002253 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Health Care Delivery, Economics and Global Health Care
Webb, Rachel
Culliford-Semmens, Nicola
ChanMow, Andrew
Doughty, Robert
Tilton, Elizabeth
Peat, Briar
Stirling, John
Gentles, Thomas L
Wilson, Nigel J
High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand
title High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand
title_full High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand
title_fullStr High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand
title_full_unstemmed High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand
title_short High burden of rheumatic heart disease confirmed by echocardiography among Pacific adults living in New Zealand
title_sort high burden of rheumatic heart disease confirmed by echocardiography among pacific adults living in new zealand
topic Health Care Delivery, Economics and Global Health Care
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186474/
https://www.ncbi.nlm.nih.gov/pubmed/37121603
http://dx.doi.org/10.1136/openhrt-2023-002253
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