Cargando…
The reverse transcriptase inhibitor 3TC protects against age‐related cognitive dysfunction
Aging is the primary risk factor for most neurodegenerative diseases, including Alzheimer's disease. Major hallmarks of brain aging include neuroinflammation/immune activation and reduced neuronal health/function. These processes contribute to cognitive dysfunction (a key risk factor for Alzhei...
Autores principales: | Wahl, Devin, Smith, Meghan E., McEntee, Cali M., Cavalier, Alyssa N., Osburn, Shelby C., Burke, Samuel D., Grant, Randy A., Nerguizian, David, Lark, Daniel S., Link, Christopher D., LaRocca, Thomas J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186603/ https://www.ncbi.nlm.nih.gov/pubmed/36949552 http://dx.doi.org/10.1111/acel.13798 |
Ejemplares similares
-
ADAR1 suppression causes interferon signaling and transposable element transcript accumulation in human astrocytes
por: McEntee, Cali M., et al.
Publicado: (2023) -
Commentary: Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury
por: McEntee, Cali M., et al.
Publicado: (2022) -
Repetitive elements as a transcriptomic marker of aging: Evidence in multiple datasets and models
por: LaRocca, Thomas J., et al.
Publicado: (2020) -
Transcriptomic Effects of Healthspan-Promoting Dietary Interventions: Current Evidence and Future Directions
por: Wahl, Devin, et al.
Publicado: (2021) -
Amyloid beta acts synergistically as a pro-inflammatory cytokine
por: LaRocca, Thomas J., et al.
Publicado: (2021)