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Características clínicas de pacientes con epilepsia atendidos en la atención primaria

OBJECTIVE. This study aimed to fill the current knowledge gap in the literature by identifying the demographic and clinical characteristics of patients with epilepsy attending primary health care (PHC). PATIENTS AND METHODS. This was a cross-sectional study involving adults (≥ 18 years of age) with...

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Autores principales: Arteaga-Rodríguez, Carlos, Menine-Kubis, Mariana, Teixeira-Arteaga, Carlos B., Hernández-Fustes, Otto J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Viguera Editores (Evidenze Group) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186714/
http://dx.doi.org/10.33588/rn.7501.2022036
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author Arteaga-Rodríguez, Carlos
Menine-Kubis, Mariana
Teixeira-Arteaga, Carlos B.
Hernández-Fustes, Otto J.
author_facet Arteaga-Rodríguez, Carlos
Menine-Kubis, Mariana
Teixeira-Arteaga, Carlos B.
Hernández-Fustes, Otto J.
author_sort Arteaga-Rodríguez, Carlos
collection PubMed
description OBJECTIVE. This study aimed to fill the current knowledge gap in the literature by identifying the demographic and clinical characteristics of patients with epilepsy attending primary health care (PHC). PATIENTS AND METHODS. This was a cross-sectional study involving adults (≥ 18 years of age) with epilepsy attending PHC from a developing country between 2015 and 2019. Demographic information and epilepsy-related data were collected. RESULTS. A total of 140 patients (51.4% male; mean [± SD] age 44.9 ± 17.8 years) were evaluated. The mean age at onset of seizures was 29.9 ± 22.9 years, with a mean evolution of 14.3±15.4 years. Focal seizures accounted for 88.57% of cases and evolved into bilateral tonic-clonic attack (45.16%). Of those that were generalized, motor seizures accounted for 81.82%, absence 9.09%, and motor + absence 9.09%. Among generalized onset motor seizures, tonic-clonic was predominant, accounting for 55.56%. Among types, focal epilepsy predominated (88.57%). The primary etiologies were unknown (62.14%), structural causes (27.85%) and infectious (9.28%). Patients undergoing monotherapy accounted for 66.1%, with epilepsy control in 92.4%. The most commonly used antiepileptic drugs were carbamazepine (33.1%), valproic acid (28.2%), and phenobarbital (10.4%). CONCLUSIONS. Male sex, seizures, and focal epilepsy were prevalent. Magnetic resonance imaging was more useful than computed tomography. Most etiologies were unknown; however, mesial temporal sclerosis and neurocysticercosis were the most prevalent known causes. Most patients were controlled using a monotherapy regimen. The implementation of International League Against Epilepsy classifications and definitions was feasible and useful
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spelling pubmed-101867142023-05-19 Características clínicas de pacientes con epilepsia atendidos en la atención primaria Arteaga-Rodríguez, Carlos Menine-Kubis, Mariana Teixeira-Arteaga, Carlos B. Hernández-Fustes, Otto J. Rev Neurol Original OBJECTIVE. This study aimed to fill the current knowledge gap in the literature by identifying the demographic and clinical characteristics of patients with epilepsy attending primary health care (PHC). PATIENTS AND METHODS. This was a cross-sectional study involving adults (≥ 18 years of age) with epilepsy attending PHC from a developing country between 2015 and 2019. Demographic information and epilepsy-related data were collected. RESULTS. A total of 140 patients (51.4% male; mean [± SD] age 44.9 ± 17.8 years) were evaluated. The mean age at onset of seizures was 29.9 ± 22.9 years, with a mean evolution of 14.3±15.4 years. Focal seizures accounted for 88.57% of cases and evolved into bilateral tonic-clonic attack (45.16%). Of those that were generalized, motor seizures accounted for 81.82%, absence 9.09%, and motor + absence 9.09%. Among generalized onset motor seizures, tonic-clonic was predominant, accounting for 55.56%. Among types, focal epilepsy predominated (88.57%). The primary etiologies were unknown (62.14%), structural causes (27.85%) and infectious (9.28%). Patients undergoing monotherapy accounted for 66.1%, with epilepsy control in 92.4%. The most commonly used antiepileptic drugs were carbamazepine (33.1%), valproic acid (28.2%), and phenobarbital (10.4%). CONCLUSIONS. Male sex, seizures, and focal epilepsy were prevalent. Magnetic resonance imaging was more useful than computed tomography. Most etiologies were unknown; however, mesial temporal sclerosis and neurocysticercosis were the most prevalent known causes. Most patients were controlled using a monotherapy regimen. The implementation of International League Against Epilepsy classifications and definitions was feasible and useful Viguera Editores (Evidenze Group) 2022-07-01 /pmc/articles/PMC10186714/ http://dx.doi.org/10.33588/rn.7501.2022036 Text en Copyright: © Revista de Neurología https://creativecommons.org/licenses/by-nc-nd/4.0/Revista de Neurología trabaja bajo una licencia Creative Commons
spellingShingle Original
Arteaga-Rodríguez, Carlos
Menine-Kubis, Mariana
Teixeira-Arteaga, Carlos B.
Hernández-Fustes, Otto J.
Características clínicas de pacientes con epilepsia atendidos en la atención primaria
title Características clínicas de pacientes con epilepsia atendidos en la atención primaria
title_full Características clínicas de pacientes con epilepsia atendidos en la atención primaria
title_fullStr Características clínicas de pacientes con epilepsia atendidos en la atención primaria
title_full_unstemmed Características clínicas de pacientes con epilepsia atendidos en la atención primaria
title_short Características clínicas de pacientes con epilepsia atendidos en la atención primaria
title_sort características clínicas de pacientes con epilepsia atendidos en la atención primaria
topic Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186714/
http://dx.doi.org/10.33588/rn.7501.2022036
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