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VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT

INTRO: Coronavirus disease (COVID-19) is currently a global health crisis and is caused by a new strain of coronavirus. However, emerging literature of case reports noted possible extrapulmonary manifestations of the disease. Because COVID 19 is a relatively new disease, at present, little existing...

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Autores principales: Gnilo, M.R., Santos, F., Cruzat, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186893/
http://dx.doi.org/10.1016/j.ijid.2023.04.197
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author Gnilo, M.R.
Santos, F.
Cruzat, K.
author_facet Gnilo, M.R.
Santos, F.
Cruzat, K.
author_sort Gnilo, M.R.
collection PubMed
description INTRO: Coronavirus disease (COVID-19) is currently a global health crisis and is caused by a new strain of coronavirus. However, emerging literature of case reports noted possible extrapulmonary manifestations of the disease. Because COVID 19 is a relatively new disease, at present, little existing literature tackles the diagnosis and therapeutic management of COVID‐19‐related conditions outside the pulmonary system. METHODS: This is a case of a 24-year-old male presented with the chief complaint of sudden stiffening of all extremities. Non-contrast computed tomography (CT) scan was unremarkable. Chest X-ray revealed interstitial pneumonia and SARS-CoV-2 RT-PCR (OPS/NPS) was positive. Electrocardiogram (ECG) findings showed supraventricular tachycardia and had elevated Troponin I levels. Pertinent physical findings noted were slurring of speech, dysmetria, and vertical nystagmus. FINDINGS: The patient was initially treated as a case of Bacterial Abscess versus Viral encephalitis. Pericardial ultrasound revealed small pericardial effusion and was started on Colchicine. Repeat cranial CT scan noted unremarkable results but due to persistence of symptoms, the patient was started with Dexamethasone. On Day 16 of illness, the patient was noted to have full resolution of symptoms. Rapid antibody testing was done which revealed positive for both IgG and IgM hence the patient was discharged with the final diagnosis of Viral Myopericarditis resolved, Viral encephalitis resolved, COVID-19 pneumonia recovered. CONCLUSION: Extrapulmonary manifestations have been reported increasingly as an atypical presentation of COVID 19 infection. Early recognition of viral myopericarditis and viral encephalitis as a manifestation of COVID 19 can lead to the initiation of proper treatment and management. More reports on these cases can aid future studies on diagnostics and therapeutic approaches during the COVID-19 pandemic.
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spelling pubmed-101868932023-05-16 VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT Gnilo, M.R. Santos, F. Cruzat, K. Int J Infect Dis Article INTRO: Coronavirus disease (COVID-19) is currently a global health crisis and is caused by a new strain of coronavirus. However, emerging literature of case reports noted possible extrapulmonary manifestations of the disease. Because COVID 19 is a relatively new disease, at present, little existing literature tackles the diagnosis and therapeutic management of COVID‐19‐related conditions outside the pulmonary system. METHODS: This is a case of a 24-year-old male presented with the chief complaint of sudden stiffening of all extremities. Non-contrast computed tomography (CT) scan was unremarkable. Chest X-ray revealed interstitial pneumonia and SARS-CoV-2 RT-PCR (OPS/NPS) was positive. Electrocardiogram (ECG) findings showed supraventricular tachycardia and had elevated Troponin I levels. Pertinent physical findings noted were slurring of speech, dysmetria, and vertical nystagmus. FINDINGS: The patient was initially treated as a case of Bacterial Abscess versus Viral encephalitis. Pericardial ultrasound revealed small pericardial effusion and was started on Colchicine. Repeat cranial CT scan noted unremarkable results but due to persistence of symptoms, the patient was started with Dexamethasone. On Day 16 of illness, the patient was noted to have full resolution of symptoms. Rapid antibody testing was done which revealed positive for both IgG and IgM hence the patient was discharged with the final diagnosis of Viral Myopericarditis resolved, Viral encephalitis resolved, COVID-19 pneumonia recovered. CONCLUSION: Extrapulmonary manifestations have been reported increasingly as an atypical presentation of COVID 19 infection. Early recognition of viral myopericarditis and viral encephalitis as a manifestation of COVID 19 can lead to the initiation of proper treatment and management. More reports on these cases can aid future studies on diagnostics and therapeutic approaches during the COVID-19 pandemic. Published by Elsevier Ltd. 2023-05 2023-05-16 /pmc/articles/PMC10186893/ http://dx.doi.org/10.1016/j.ijid.2023.04.197 Text en Copyright © 2023 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Gnilo, M.R.
Santos, F.
Cruzat, K.
VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT
title VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT
title_full VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT
title_fullStr VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT
title_full_unstemmed VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT
title_short VIRAL MYOPERICARDITIS AND VIRAL ENCEPHALITIS AS MANIFESTATIONS OF COVID-19 INFECTION: A CASE REPORT
title_sort viral myopericarditis and viral encephalitis as manifestations of covid-19 infection: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186893/
http://dx.doi.org/10.1016/j.ijid.2023.04.197
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