Molecular choreography of primer synthesis by the eukaryotic Pol α-primase

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The eukaryotic polymerase α (Pol α) is a dual-function DNA polymerase/primase complex that synthesizes an RNA-DNA hybrid primer of 20–30 nucleotides for DNA replication. Pol α is composed of Pol1, Pol12, Primase 1 (Pri1), and Pri2, with Pol1 and Pri1 containing the DNA polymerase activity and RNA pr...

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Detalles Bibliográficos
Autores principales: Yuan, Zuanning, Georgescu, Roxana, Li, Huilin, O’Donnell, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187153/
https://www.ncbi.nlm.nih.gov/pubmed/37205351
http://dx.doi.org/10.1101/2023.05.03.539257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187153/
https://www.ncbi.nlm.nih.gov/pubmed/37205351
http://dx.doi.org/10.1101/2023.05.03.539257

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