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Host-cell Interactions of Engineered T cell Micropharmacies

Genetically engineered, cytotoxic, adoptive T cells localize to antigen positive cancer cells inside patients, but tumor heterogeneity and multiple immune escape mechanisms have prevented the eradication of most solid tumor types. More effective, multifunctional engineered T cells are in development...

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Detalles Bibliográficos
Autores principales: Bourne, Christopher M., Wallisch, Patrick, Dacek, Megan, Gardner, Thomas, Pierre, Stephanie, Vogt, Kristen, Corless, Broderick C., Bah, Mamadou A., Romero Pichardo, Jesus, Charles, Angel, Kurtz, Keifer G., Tan, Derek S., Scheinberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187158/
https://www.ncbi.nlm.nih.gov/pubmed/37205431
http://dx.doi.org/10.1101/2023.04.05.535717