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Host-cell Interactions of Engineered T cell Micropharmacies
Genetically engineered, cytotoxic, adoptive T cells localize to antigen positive cancer cells inside patients, but tumor heterogeneity and multiple immune escape mechanisms have prevented the eradication of most solid tumor types. More effective, multifunctional engineered T cells are in development...
Autores principales: | Bourne, Christopher M., Wallisch, Patrick, Dacek, Megan, Gardner, Thomas, Pierre, Stephanie, Vogt, Kristen, Corless, Broderick C., Bah, Mamadou A., Romero Pichardo, Jesus, Charles, Angel, Kurtz, Keifer G., Tan, Derek S., Scheinberg, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187158/ https://www.ncbi.nlm.nih.gov/pubmed/37205431 http://dx.doi.org/10.1101/2023.04.05.535717 |
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