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Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway

Several signaling pathways are activated during hypoxia to promote angiogenesis, leading to endothelial cell patterning, interaction, and downstream signaling. Understanding the mechanistic signaling differences between normoxia and hypoxia can guide therapies to modulate angiogenesis. We present a...

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Detalles Bibliográficos
Autores principales: Oliveira, Rebeca Hannah M, Annex, Brian H., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187169/
https://www.ncbi.nlm.nih.gov/pubmed/37205581
http://dx.doi.org/10.1101/2023.05.03.539270

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