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Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein

Molecular interactions between viral DNA and viral-encoded protein are a prerequisite for successful herpesvirus replication and production of new infectious virions. Here, we examined how the essential Kaposi’s sarcoma-associated herpesvirus (KSHV) protein, RTA, binds to viral DNA using transmissio...

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Detalles Bibliográficos
Autores principales: Calhoun, Jayla C., Damania, Blossom, Griffith, Jack D., Costantini, Lindsey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187201/
https://www.ncbi.nlm.nih.gov/pubmed/37205529
http://dx.doi.org/10.1101/2023.05.01.538939