High-content microscopy reveals a morphological signature of bortezomib resistance

Drug resistance is a challenge in anticancer therapy, particularly with targeted therapeutics and cytotoxic compounds. In many cases, cancers can be resistant to the drug prior to exposure, i.e., possess intrinsic drug resistance. However, we lack target-independent methods to anticipate resistance...

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Detalles Bibliográficos
Autores principales: Kelley, M.E., Berman, A.Y., Stirling, D.R., Cimini, B.A., Han, Y., Singh, S., Carpenter, A.E., Kapoor, T.M., Way, G.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187224/
https://www.ncbi.nlm.nih.gov/pubmed/37205516
http://dx.doi.org/10.1101/2023.05.02.539137

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