Cargando…
Modification of the Neck Linker of KIF18A Alters Microtubule Subpopulation Preference
Kinesins support many diverse cellular processes, including facilitating cell division through mechanical regulation of the mitotic spindle. However, how kinesin activity is controlled to facilitate this process is not well understood. Interestingly, post-translational modifications have been identi...
Autores principales: | Queen, Katelyn A., Cario, Alisa, Berger, Christopher L., Stumpff, Jason |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187232/ https://www.ncbi.nlm.nih.gov/pubmed/37205510 http://dx.doi.org/10.1101/2023.05.02.539080 |
Ejemplares similares
-
KIF18A's neck linker permits navigation of microtubule-bound obstacles within the mitotic spindle
por: Malaby, Heidi LH, et al.
Publicado: (2019) -
Chromosomally unstable tumor cells specifically require KIF18A for proliferation
por: Marquis, Carolyn, et al.
Publicado: (2021) -
Identification of the KIF18A alpha-4 helix as a therapeutic target for chromosomally unstable tumor cells
por: Schutt, Katherine, et al.
Publicado: (2023) -
Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15
por: Malaby, Heidi L.H., et al.
Publicado: (2019) -
Glucose-stimulated KIF5B-driven microtubule sliding organizes microtubule networks in pancreatic beta cells
por: Bracey, Kai M., et al.
Publicado: (2023)