Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior

BACKGROUND: Major depressive disorder (MDD), along with related mood disorders, is a debilitating illness that affects millions of individuals worldwide. While chronic stress increases incidence levels of mood disorders, stress-mediated disruptions in brain function that precipitate these illnesses...

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Detalles Bibliográficos
Autores principales: Al-Kachak, Amni, Fulton, Sasha L., Di Salvo, Giuseppina, Chan, Jennifer C, Farrelly, Lorna A., Lepack, Ashley E., Bastle, Ryan M., Kong, Lingchun, Cathomas, Flurin, Newman, Emily L., Menard, Caroline, Ramakrishnan, Aarthi, Safovich, Polina, Lyu, Yang, Covington, Herbert E., Shen, Li, Gleason, Kelly, Tamminga, Carol A., Russo, Scott J., Maze, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187276/
https://www.ncbi.nlm.nih.gov/pubmed/37205414
http://dx.doi.org/10.1101/2023.05.04.539464

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