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VERY LONG-CHAIN ACYL-CoA SYNTHETASE-3 (ACSVL3) PROMOTES THE MALIGNANT GROWTH BEHAVIOR OF U87 GLIOMA CELLS VIA CHANGES IN CELL CYCLE WITHOUT AFFECTING APOPTOSIS

Decreasing the expression of very long-chain acyl-CoA synthetase 3 (ACSVL3) in U87MG glioblastoma cells by either RNA interference or genomic knockout (KO) significantly decreased their growth rate in culture, as well as their ability to form rapidly growing tumors in mice. U87-KO cells grew at a 9-...

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Detalles Bibliográficos
Autores principales:	Yang, Haiyan, Shi, Xiaohai, Kolar, Elizabeth A., Clay, Emily M., Xia, Shuli, Pei, Zhengtong, Watkins, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187290/ https://www.ncbi.nlm.nih.gov/pubmed/37205435 http://dx.doi.org/10.1101/2023.05.04.539403

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