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TLR priming licenses NAIP inflammasome activation by immunoevasive ligands

NLR family, apoptosis inhibitory proteins (NAIPs) detect bacterial flagellin and structurally related components of bacterial type III secretion systems (T3SS), and recruit NLR family, CARD domain containing protein 4 (NLRC4) and caspase-1 into an inflammasome complex that induces pyroptosis. NAIP/N...

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Detalles Bibliográficos
Autores principales:	Grayczyk, James P., Egan, Marisa S., Liu, Luying, Aunins, Emily, Wynosky-Dolfi, Meghan A., Canna, Scott, Minn, Andy J., Shin, Sunny, Brodsky, Igor E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187295/ https://www.ncbi.nlm.nih.gov/pubmed/37205371 http://dx.doi.org/10.1101/2023.05.04.539437

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