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Genetic control of the error-prone repair of a chromosomal double-strand break with 5’ overhangs in yeast
A targeted double-strand break introduced into the genome of Saccharomyces cerevisiae is repaired by the relatively error-prone nonhomologous-end joining (NHEJ) pathway when homologous recombination is not an option. A ZFN cleavage site was inserted out-of-frame into the LYS2 locus of a haploid yeas...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187297/ https://www.ncbi.nlm.nih.gov/pubmed/37205473 http://dx.doi.org/10.1101/2023.05.04.539391 |