Cargando…

B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage

Stalled ribosomes are rescued by pathways that recycle the ribosome and target the nascent polypeptide for degradation. In E. coli, these pathways are triggered by ribosome collisions through recruitment of SmrB, a nuclease that cleaves the mRNA. In B. subtilis, the related protein MutS2 was recentl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Esther, Mackens-Kiani, Timur, Berhane, Rebekah, Esser, Hanna, Erdenebat, Chimeg, Burroughs, A. Maxwell, Berninghausen, Otto, Aravind, L., Beckmann, Roland, Green, Rachel, Buskirk, Allen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187299/ https://www.ncbi.nlm.nih.gov/pubmed/37205477 http://dx.doi.org/10.1101/2023.05.05.539626

Ejemplares similares

Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling
por: Sohmen, Daniel, et al.
Publicado: (2015)

The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains
por: Knorr, Alexandra G., et al.
Publicado: (2023)

Structure of Gcn1 bound to stalled and colliding 80S ribosomes
por: Pochopien, Agnieszka A., et al.
Publicado: (2021)

Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes
por: Wells, Jennifer N., et al.
Publicado: (2020)

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center
por: Bhushan, Shashi, et al.
Publicado: (2011)

A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes
por: Kratzat, Hanna, et al.
Publicado: (2020)

Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes
por: Weaver, Jeremy, et al.
Publicado: (2019)

The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling
por: Su, Ting, et al.
Publicado: (2017)

Ubiquitination of stalled ribosome triggers ribosome-associated quality control
por: Matsuo, Yoshitaka, et al.
Publicado: (2017)

The SmpB C-terminal tail helps tmRNA to recognize and enter stalled ribosomes
por: Miller, Mickey R., et al.
Publicado: (2014)

Vms1/Ankzf1 peptidyl-tRNA hydrolase releases nascent chains from stalled ribosomes
por: Verma, Rati, et al.
Publicado: (2018)

SMG-6 mRNA cleavage stalls ribosomes near premature stop codons in vivo
por: Kim, John H, et al.
Publicado: (2022)

Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post‐splitting complex
por: Nürenberg‐Goloub, Elina, et al.
Publicado: (2020)

Ribosome-associated Asc1/RACK1 is required for endonucleolytic cleavage induced by stalled ribosome at the 3′ end of nonstop mRNA
por: Ikeuchi, Ken, et al.
Publicado: (2016)

A ribosome profiling study of mRNA cleavage by the endonuclease RelE
por: Hwang, Jae-Yeon, et al.
Publicado: (2017)

Rejection of tmRNA·SmpB after GTP hydrolysis by EF-Tu on ribosomes stalled on intact mRNA
por: Kurita, Daisuke, et al.
Publicado: (2014)

The mismatch recognition protein MutSα promotes nascent strand degradation at stalled replication forks
por: Zhang, Junqiu, et al.
Publicado: (2022)

Loss of N(1)-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression
por: Masuda, Isao, et al.
Publicado: (2021)

Human NMD ensues independently of stable ribosome stalling
por: Karousis, Evangelos D., et al.
Publicado: (2020)

The deubiquitylase USP9X controls ribosomal stalling
por: Clancy, Anne, et al.
Publicado: (2021)

In vitro Analysis of Stalled Ribosomes Using Puromycin Incorporation
por: Scarpitti, MaKenzie R., et al.
Publicado: (2023)

Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress
por: Stoneley, Mark, et al.
Publicado: (2022)

The fail-safe system to rescue the stalled ribosomes in Escherichia coli
por: Abo, Tatsuhiko, et al.
Publicado: (2014)

Mechanisms of ribosome stalling by SecM at multiple elongation steps
por: Zhang, Jun, et al.
Publicado: (2015)

The Ribosome Restrains Molten Globule Formation in Stalled Nascent Flavodoxin
por: Houwman, Joseline A., et al.
Publicado: (2016)

Toxin-mediated ribosome stalling reprograms the Mycobacterium tuberculosis proteome
por: Barth, Valdir C., et al.
Publicado: (2019)

CAT tails drive degradation of stalled polypeptides on and off the ribosome
por: Sitron, Cole S., et al.
Publicado: (2019)

Correction: The deubiquitylase USP9X controls ribosomal stalling
por: Clancy, Anne, et al.
Publicado: (2021)

Translational buffering by ribosome stalling in upstream open reading frames
por: Bottorff, Ty A., et al.
Publicado: (2022)

Ribosome Stalling of N-Linked Glycoproteins in Cell-Free Extracts
por: Chung, Sean S., et al.
Publicado: (2022)

Identification of factors that prevent ribosome stalling during early elongation
por: Hye-Rim, Hong, et al.
Publicado: (2023)

Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast
por: Rubio, Angela, et al.
Publicado: (2020)

Mechanisms of RNAi: mRNA cleavage fragments may indicate stalled RISC
por: Holen, Torgeir
Publicado: (2005)

NusG-Dependent RNA Polymerase Pausing and Tylosin-Dependent Ribosome Stalling Are Required for Tylosin Resistance by Inducing 23S rRNA Methylation in Bacillus subtilis
por: Yakhnin, Helen, et al.
Publicado: (2019)

Cellular response to small molecules that selectively stall protein synthesis by the ribosome
por: Liaud, Nadège, et al.
Publicado: (2019)

Recent Progress on the Molecular Mechanism of Quality Controls Induced by Ribosome Stalling
por: Ikeuchi, Ken, et al.
Publicado: (2019)

ArfB can displace mRNA to rescue stalled ribosomes
por: Carbone, Christine E., et al.
Publicado: (2020)

Mechanism of ribosome stalling during translation of a poly(A) tail
por: Chandrasekaran, Viswanathan, et al.
Publicado: (2019)

Caveolar communication with xenobiotic-stalled ribosomes compromises gut barrier integrity
por: Park, Seong-Hwan, et al.
Publicado: (2020)

Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling
por: van der Stel, Anne-Xander, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ov8anuveeocbvqd3paf3ll1ruf