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Soluble antigen arrays improve the efficacy and safety of peptide-based tolerogenic immunotherapy

Autoantigen-specific immunotherapy using peptides offers a more targeted approach to treat autoimmune diseases, but the limited in vivo stability and uptake of peptides impedes clinical implementation. We previously showed that multivalent delivery of peptides as soluble antigen arrays (SAgAs) effic...

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Detalles Bibliográficos
Autores principales:	Firdessa-Fite, Rebuma, Johnson, Stephanie N., Leon, Martin A., Sestak, Joshua O., Berkland, Cory, Creusot, Remi J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187310/ https://www.ncbi.nlm.nih.gov/pubmed/37205572 http://dx.doi.org/10.1101/2023.05.05.539161

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