Organoid modeling of lung-resident immune responses to SARS-CoV-2 infection

Tissue-resident immunity underlies essential host defenses against pathogens, but analysis in humans has lacked in vitro model systems where epithelial infection and accompanying resident immune cell responses can be observed en bloc. Indeed, human primary epithelial organoid cultures typically omit...

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Detalles Bibliográficos
Autores principales: Choi, Shannon S., van Unen, Vincent, Zhang, Huimin, Rustagi, Arjun, Alwahabi, Samira A., Santos, António J.M., Chan, Joshua E., Lam, Brandon, Solis, Daniel, Mah, Jordan, Röltgen, Katharina, Trope, Winston, Guh-Siesel, Alexander, Lin, Zhongqi, Beck, Aimee, Edwards, Caitlin, Mallajosyula, Vamsee, Martin, Brock A., Dunn, James C. Y., Shrager, Joseph, Baric, Ralph A., Pinsky, Benjamin, Boyd, Scott D., Blish, Catherine A., Davis, Mark M., Kuo, Calvin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187413/
https://www.ncbi.nlm.nih.gov/pubmed/37205380
http://dx.doi.org/10.21203/rs.3.rs-2870695/v1

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