Transcriptomic signature, bioactivity and safety of a non-hepatoxic analgesic generating AM404 in the mid-brain PAG region

The safe and effective management of pain is a critical healthcare and societal need. The potential for misuse and addiction associated with opioids, nephrotoxicity, and gastrointestinal damage from chronic non-steroidal anti-inflammatory drug (NSAID) use, as well as acute liver injury from paraceta...

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Detalles Bibliográficos
Autores principales: Bazan, Hernan, Bhattacharjee, Surjyadipta, Reid, Madigan, Jun, Bokkyoo, Polk, Connor, Strain, Madeleine, Pierre, Linsey St, Desai, Neehar, Daly, Patrick, Cucinello-Ragland, Jessica, Edwards, Scott, Alvarez-Builla, Julio, Cai, James, Bazan, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187420/
https://www.ncbi.nlm.nih.gov/pubmed/37205420
http://dx.doi.org/10.21203/rs.3.rs-2883310/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187420/
https://www.ncbi.nlm.nih.gov/pubmed/37205420
http://dx.doi.org/10.21203/rs.3.rs-2883310/v1

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