Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation

Fuchs endothelial corneal dystrophy (FECD) is a leading indication for corneal transplantation, but its molecular pathophysiology remains poorly understood. We performed genome-wide association studies (GWAS) of FECD in the Million Veteran Program (MVP) and meta-analyzed with the previous largest FE...

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Detalles Bibliográficos
Autores principales: Peachey, Neal, Gorman, Bryan, Francis, Michael, Nealon, Cari, Halladay, Christopher, Duro, Nalvi, Markianos, Kyriacos, Genovese, Giulio, Hysi, Pirro, Choquet, Hélène, Afshari, Natalie, Li, Yi-Ju, Gaziano, J. Michael, Hung, Adriana, Wu, Wen-Chih, Greenberg, Paul, Pyarajan, Saiju, Lass, Jonathan, Iyengar, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187421/
https://www.ncbi.nlm.nih.gov/pubmed/37205546
http://dx.doi.org/10.21203/rs.3.rs-2762003/v1

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