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Characterization of autoimmune eye disease in association with Down's Syndrome
BACKGROUND: Autoimmunity and deficiency of the transcription factor autoimmune regulator protein (AIRE) are known associations with Down Syndrome (DS). Lack of AIRE abrogates thymic tolerance. The autoimmune eye disease associated with DS has not been characterized. We identified a series of subject...
Autores principales: | Rosenbaum, James, Zaki, Amr, Pasadhika, Sirichai, Huang, Jerry, Thomas, Akshay, Burkholder, Bryn, Lim, Lyndell, Llop, Stephanie, Suhler, Eric, Adamus, Grazyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187437/ https://www.ncbi.nlm.nih.gov/pubmed/37205347 http://dx.doi.org/10.21203/rs.3.rs-2766021/v1 |
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