Indoleamine 2,3-Dioxygenase: A Novel Immunotherapeutic Target for Osteosarcoma

INTRODUCTION: Tumour-emitted molecules induce immunosuppression in the tumour microenvironment. An immunosuppressive enzyme, indoleamine 2,3-dioxygenase (IDO/IDO1), facilitates immune escape in several malignant tumours, including osteosarcoma. Upregulation of IDO establishes a tolerogenic environme...

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Detalles Bibliográficos
Autores principales: Farooq, Asim, Zulfiqar, Bilal, Asghar, Kashif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore. Pakistan 2023
Materias:
Systematic Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187603/
https://www.ncbi.nlm.nih.gov/pubmed/37197000
http://dx.doi.org/10.37029/jcas.v9i1.501

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