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Immune Profiling Panel Gene Set Identifies Critically Ill Patients With Low Monocyte Human Leukocyte Antigen-DR Expression: Preliminary Results From the REAnimation Low Immune Status Marker (REALISM) Study

There is a crucial unmet need for biomarker-guided diagnostic and prognostic enrichment in clinical trials evaluating immune modulating therapies in critically ill patients. Low monocyte expression of human leukocyte antigen-DR (mHLA-DR), considered as a reference surrogate to identify immunosuppres...

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Detalles Bibliográficos
Autores principales: Peronnet, Estelle, Blein, Sophie, Venet, Fabienne, Cerrato, Elisabeth, Fleurie, Aurore, Llitjos, Jean-François, Kreitmann, Louis, Terraz, Gabriel, Conti, Filippo, Gossez, Morgane, Rimmelé, Thomas, Textoris, Julien, Lukaszewicz, Anne-Claire, Brengel-Pesce, Karen, Monneret, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187625/
https://www.ncbi.nlm.nih.gov/pubmed/36917594
http://dx.doi.org/10.1097/CCM.0000000000005832