Sexual Dimorphism in Brain Sirtuin-1 and m6A Methylated Sirtuin-1 mRNA, and in Protection with Post-Injury Anti-miR-200c treatment, after Experimental Stroke in Aged Mice

We previously demonstrated that inhibition of miR-200c was protective against stroke in young adult male mice by augmenting sirtuin-1 (Sirt1). In the present study we assessed the role of miR-200c on injury, Sirt1, and bioenergetic and neuroinflammatory markers in aged male and female mice after exp...

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Detalles Bibliográficos
Autores principales: Xu, Lijun, Sun, Xiaoyun, Griffiths, Brian, Voloboueva, Ludmilla, Valdes, Alex, Dobrenski, Miles, Min, Jeong-Jin, Stary, Creed M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187686/
https://www.ncbi.nlm.nih.gov/pubmed/37191419
http://dx.doi.org/10.14336/AD.2022.1225

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