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The future of targeted kinase inhibitors in melanoma

Melanoma is a cancer of the pigment-producing cells of the body and its incidence is rising. Targeted inhibitors that act against kinases in the MAPK pathway are approved for BRAF-mutant metastatic cutaneous melanoma and increase patients’ survival. Response to these therapies is limited by drug res...

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Detalles Bibliográficos
Autores principales: Caksa, Signe, Baqai, Usman, Aplin, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187889/
https://www.ncbi.nlm.nih.gov/pubmed/35513054
http://dx.doi.org/10.1016/j.pharmthera.2022.108200