Cargando…
The future of targeted kinase inhibitors in melanoma
Melanoma is a cancer of the pigment-producing cells of the body and its incidence is rising. Targeted inhibitors that act against kinases in the MAPK pathway are approved for BRAF-mutant metastatic cutaneous melanoma and increase patients’ survival. Response to these therapies is limited by drug res...
Autores principales: | Caksa, Signe, Baqai, Usman, Aplin, Andrew E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187889/ https://www.ncbi.nlm.nih.gov/pubmed/35513054 http://dx.doi.org/10.1016/j.pharmthera.2022.108200 |
Ejemplares similares
-
Gene signature reveals decreased SOX10-dependent transcripts in malignant cells from immune checkpoint inhibitor-resistant cutaneous melanomas
por: Purwin, Timothy J., et al.
Publicado: (2023) -
SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects
por: Rosenbaum, Sheera R., et al.
Publicado: (2021) -
Mechanisms of resistance to RAF inhibitors in melanoma
por: Aplin, Andrew E., et al.
Publicado: (2011) -
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma
por: Capparelli, Claudia, et al.
Publicado: (2022) -
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth
por: Han, Anna, et al.
Publicado: (2023)