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Characterization of a pathway of genomic instability induced by R-loops and its regulation by topoisomerases in E. coli
The prototype enzymes of the ubiquitous type IA topoisomerases (topos) family are Escherichia coli topo I (topA) and topo III (topB). Topo I shows preference for relaxation of negative supercoiling and topo III for decatenation. However, as they could act as backups for each other or even share func...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187895/ https://www.ncbi.nlm.nih.gov/pubmed/37141391 http://dx.doi.org/10.1371/journal.pgen.1010754 |