Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1

Next generation sequencing of human cancer mutations has identified novel therapeutic targets. Activating Ras oncogene mutations play a central role in oncogenesis, and Ras-driven tumorigenesis upregulates an array of genes and signaling cascades that can transform normal cells into tumor cells. In...

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Detalles Bibliográficos
Autores principales: Omar, Fatma A., Brown, Taylor C., Gillanders, William E., Fleming, Timothy P., Smith, Michael A., Bremner, Ross M., Sankpal, Narendra V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187930/
https://www.ncbi.nlm.nih.gov/pubmed/37192201
http://dx.doi.org/10.1371/journal.pone.0285707

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