A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma

Juvenile xanthogranuloma (JXG) is an uncommon benign skin disorder of infants and young children characterized by dermal proliferation and infiltration of dendrocytes. We present a unique case of giant congenital JXG with a mixed presentation of macules, papules, nodules, and ulcerations in a neonat...

Descripción completa

Detalles Bibliográficos
Autores principales: Malana, Erika, Kowalski, Paul, Gallagher, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187945/
https://www.ncbi.nlm.nih.gov/pubmed/37200655
http://dx.doi.org/10.7759/cureus.37644
_version_ 1785042825441705984
author Malana, Erika
Kowalski, Paul
Gallagher, Michelle
author_facet Malana, Erika
Kowalski, Paul
Gallagher, Michelle
author_sort Malana, Erika
collection PubMed
description Juvenile xanthogranuloma (JXG) is an uncommon benign skin disorder of infants and young children characterized by dermal proliferation and infiltration of dendrocytes. We present a unique case of giant congenital JXG with a mixed presentation of macules, papules, nodules, and ulcerations in a neonatal male who was observed until the age of 23 months, by which time all lesions had spontaneously self-involuted. Prior to complete resolution, some lesions took the form of pedunculated protrusions. To our knowledge, this is the first of this atypical case to be presented in the literature.
format Online
Article
Text
id pubmed-10187945
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-101879452023-05-17 A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma Malana, Erika Kowalski, Paul Gallagher, Michelle Cureus Dermatology Juvenile xanthogranuloma (JXG) is an uncommon benign skin disorder of infants and young children characterized by dermal proliferation and infiltration of dendrocytes. We present a unique case of giant congenital JXG with a mixed presentation of macules, papules, nodules, and ulcerations in a neonatal male who was observed until the age of 23 months, by which time all lesions had spontaneously self-involuted. Prior to complete resolution, some lesions took the form of pedunculated protrusions. To our knowledge, this is the first of this atypical case to be presented in the literature. Cureus 2023-04-16 /pmc/articles/PMC10187945/ /pubmed/37200655 http://dx.doi.org/10.7759/cureus.37644 Text en Copyright © 2023, Malana et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Malana, Erika
Kowalski, Paul
Gallagher, Michelle
A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma
title A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma
title_full A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma
title_fullStr A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma
title_full_unstemmed A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma
title_short A Case of Multiple Self-Involuting, Mixed Presentation, Giant Congenital Juvenile Xanthogranuloma
title_sort case of multiple self-involuting, mixed presentation, giant congenital juvenile xanthogranuloma
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187945/
https://www.ncbi.nlm.nih.gov/pubmed/37200655
http://dx.doi.org/10.7759/cureus.37644
work_keys_str_mv AT malanaerika acaseofmultipleselfinvolutingmixedpresentationgiantcongenitaljuvenilexanthogranuloma
AT kowalskipaul acaseofmultipleselfinvolutingmixedpresentationgiantcongenitaljuvenilexanthogranuloma
AT gallaghermichelle acaseofmultipleselfinvolutingmixedpresentationgiantcongenitaljuvenilexanthogranuloma
AT malanaerika caseofmultipleselfinvolutingmixedpresentationgiantcongenitaljuvenilexanthogranuloma
AT kowalskipaul caseofmultipleselfinvolutingmixedpresentationgiantcongenitaljuvenilexanthogranuloma
AT gallaghermichelle caseofmultipleselfinvolutingmixedpresentationgiantcongenitaljuvenilexanthogranuloma

Ejemplares similares