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Histological observations on aural fibrosarcoma in a Holstein cow

Fibrosarcomas occur as a mesenchymal tumour of malignant fibroblasts in a collagen background and are usually found in the female genital organs and rarely involve the skin. A 5‐year‐old female Holstein cow with a raised mass at the base of right ear was referred. On gross examination, the mass was...

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Autores principales: Shokrpoor, Sara, Gorjidooz, Morteza, Azizi, Peyman, Ghamsari, Seyed Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188069/
https://www.ncbi.nlm.nih.gov/pubmed/36944027
http://dx.doi.org/10.1002/vms3.1126
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author Shokrpoor, Sara
Gorjidooz, Morteza
Azizi, Peyman
Ghamsari, Seyed Mehdi
author_facet Shokrpoor, Sara
Gorjidooz, Morteza
Azizi, Peyman
Ghamsari, Seyed Mehdi
author_sort Shokrpoor, Sara
collection PubMed
description Fibrosarcomas occur as a mesenchymal tumour of malignant fibroblasts in a collagen background and are usually found in the female genital organs and rarely involve the skin. A 5‐year‐old female Holstein cow with a raised mass at the base of right ear was referred. On gross examination, the mass was approximately 13.00 × 10.00 × 7.00 cm in size. Finally, complete surgical removal was selected. The mass was encapsulated and the dermis was expanded by spindle‐shaped to polygonal neoplastic cells. These cells were arranged in interwoven pattern. Mitotic figures were infrequent. Masson's trichrome demonstrated the positive and blue staining of collagen. Immunohistochemically, the sections were uniformly positive for Vimentin and negative for Desmin, SMA and GFAP. A well‐differentiated fibrosarcoma was diagnosed based on histopathological features. Surgical excision is the treatment of choice for this neoplasm. In the present case, surgery was also performed successfully and no new growth of the mass was observed 4 months following the surgical procedures. To our knowledge, this is the first report of well‐differentiated fibrosarcoma in a Holstein cow.
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spelling pubmed-101880692023-05-17 Histological observations on aural fibrosarcoma in a Holstein cow Shokrpoor, Sara Gorjidooz, Morteza Azizi, Peyman Ghamsari, Seyed Mehdi Vet Med Sci RUMINANTS Fibrosarcomas occur as a mesenchymal tumour of malignant fibroblasts in a collagen background and are usually found in the female genital organs and rarely involve the skin. A 5‐year‐old female Holstein cow with a raised mass at the base of right ear was referred. On gross examination, the mass was approximately 13.00 × 10.00 × 7.00 cm in size. Finally, complete surgical removal was selected. The mass was encapsulated and the dermis was expanded by spindle‐shaped to polygonal neoplastic cells. These cells were arranged in interwoven pattern. Mitotic figures were infrequent. Masson's trichrome demonstrated the positive and blue staining of collagen. Immunohistochemically, the sections were uniformly positive for Vimentin and negative for Desmin, SMA and GFAP. A well‐differentiated fibrosarcoma was diagnosed based on histopathological features. Surgical excision is the treatment of choice for this neoplasm. In the present case, surgery was also performed successfully and no new growth of the mass was observed 4 months following the surgical procedures. To our knowledge, this is the first report of well‐differentiated fibrosarcoma in a Holstein cow. John Wiley and Sons Inc. 2023-03-21 /pmc/articles/PMC10188069/ /pubmed/36944027 http://dx.doi.org/10.1002/vms3.1126 Text en © 2023 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle RUMINANTS
Shokrpoor, Sara
Gorjidooz, Morteza
Azizi, Peyman
Ghamsari, Seyed Mehdi
Histological observations on aural fibrosarcoma in a Holstein cow
title Histological observations on aural fibrosarcoma in a Holstein cow
title_full Histological observations on aural fibrosarcoma in a Holstein cow
title_fullStr Histological observations on aural fibrosarcoma in a Holstein cow
title_full_unstemmed Histological observations on aural fibrosarcoma in a Holstein cow
title_short Histological observations on aural fibrosarcoma in a Holstein cow
title_sort histological observations on aural fibrosarcoma in a holstein cow
topic RUMINANTS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188069/
https://www.ncbi.nlm.nih.gov/pubmed/36944027
http://dx.doi.org/10.1002/vms3.1126
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