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Copy number alteration features in pan-cancer homologous recombination deficiency prediction and biology

Homologous recombination deficiency (HRD) renders cancer cells vulnerable to unrepaired double-strand breaks and is an important therapeutic target as exemplified by the clinical efficacy of poly ADP-ribose polymerase (PARP) inhibitors as well as the platinum chemotherapy drugs applied to HRD patien...

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Detalles Bibliográficos
Autores principales:	Yao, Huizi, Li, Huimin, Wang, Jinyu, Wu, Tao, Ning, Wei, Diao, Kaixuan, Wu, Chenxu, Wang, Guangshuai, Tao, Ziyu, Zhao, Xiangyu, Chen, Jing, Sun, Xiaoqin, Liu, Xue-Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188435/ https://www.ncbi.nlm.nih.gov/pubmed/37193789 http://dx.doi.org/10.1038/s42003-023-04901-3

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