The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S

The quantification of haemoglobin A(2) by high‐performance liquid chromatography (HPLC) was compared with quantification by capillary electrophoresis for control subjects and patients with sickle cell trait or sickle cell anaemia. Significant differences were found, with estimated values being highe...

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Detalles Bibliográficos
Autores principales: Myburgh, Jane K., Szydlo, Richard M., Bain, Barbara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188449/
https://www.ncbi.nlm.nih.gov/pubmed/37206262
http://dx.doi.org/10.1002/jha2.691
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author Myburgh, Jane K.
Szydlo, Richard M.
Bain, Barbara J.
author_facet Myburgh, Jane K.
Szydlo, Richard M.
Bain, Barbara J.
author_sort Myburgh, Jane K.
collection PubMed
description The quantification of haemoglobin A(2) by high‐performance liquid chromatography (HPLC) was compared with quantification by capillary electrophoresis for control subjects and patients with sickle cell trait or sickle cell anaemia. Significant differences were found, with estimated values being higher by HPLC for control subjects and higher by capillary electrophoresis for sickle cell trait and sickle cell anaemia patients. There is an ongoing need for improved standardisation and alignment of methods.
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spelling pubmed-101884492023-05-18 The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S Myburgh, Jane K. Szydlo, Richard M. Bain, Barbara J. EJHaem Short Reports The quantification of haemoglobin A(2) by high‐performance liquid chromatography (HPLC) was compared with quantification by capillary electrophoresis for control subjects and patients with sickle cell trait or sickle cell anaemia. Significant differences were found, with estimated values being higher by HPLC for control subjects and higher by capillary electrophoresis for sickle cell trait and sickle cell anaemia patients. There is an ongoing need for improved standardisation and alignment of methods. John Wiley and Sons Inc. 2023-04-17 /pmc/articles/PMC10188449/ /pubmed/37206262 http://dx.doi.org/10.1002/jha2.691 Text en © 2023 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Reports
Myburgh, Jane K.
Szydlo, Richard M.
Bain, Barbara J.
The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S
title The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S
title_full The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S
title_fullStr The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S
title_full_unstemmed The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S
title_short The accuracy of haemoglobin A(2) measurements in the presence and absence of haemoglobin S
title_sort accuracy of haemoglobin a(2) measurements in the presence and absence of haemoglobin s
topic Short Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188449/
https://www.ncbi.nlm.nih.gov/pubmed/37206262
http://dx.doi.org/10.1002/jha2.691
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