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SARS‐CoV‐2 infection results in upregulation of Plasminogen Activator Inhibitor‐1 and Neuroserpin in the lungs, and an increase in fibrinolysis inhibitors associated with disease severity

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection results in coagulation activation although it is usually not associated with consumption coagulopathy. D‐dimers are also commonly elevated despite systemic hypofibrinolysis. To understand these unusual features of coronavirus dis...

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Detalles Bibliográficos
Autores principales: Toomer, Kevin H., Gerber, Gloria F., Zhang, Yifan, Daou, Laetitia, Tushek, Michael, Hooper, Jody E., Francischetti, Ivo M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188457/
https://www.ncbi.nlm.nih.gov/pubmed/37206290
http://dx.doi.org/10.1002/jha2.654