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A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides
Parkinson’s disease (PD) is a complex neurodegenerative disease with etiology rooted in genetic vulnerability and environmental factors. Here we combine quantitative epidemiologic study of pesticide exposures and PD with toxicity screening in dopaminergic neurons derived from PD patient induced plur...
Autores principales: | Paul, Kimberly C., Krolewski, Richard C., Lucumi Moreno, Edinson, Blank, Jack, Holton, Kristina M., Ahfeldt, Tim, Furlong, Melissa, Yu, Yu, Cockburn, Myles, Thompson, Laura K., Kreymerman, Alexander, Ricci-Blair, Elisabeth M., Li, Yu Jun, Patel, Heer B., Lee, Richard T., Bronstein, Jeff, Rubin, Lee L., Khurana, Vikram, Ritz, Beate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188516/ https://www.ncbi.nlm.nih.gov/pubmed/37193692 http://dx.doi.org/10.1038/s41467-023-38215-z |
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