PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity

Activation of the cGAS/STING innate immunity pathway is essential and effective for anti-tumor immunotherapy. However, it remains largely elusive how tumor-intrinsic cGAS signaling is suppressed to facilitate tumorigenesis by escaping immune surveillance. Here, we report that the protein arginine me...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Bu, Xia, Chu, Chen, Dai, Xiaoming, Asara, John M., Sicinski, Piotr, Freeman, Gordon J., Wei, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188589/
https://www.ncbi.nlm.nih.gov/pubmed/37193698
http://dx.doi.org/10.1038/s41467-023-38443-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188589/
https://www.ncbi.nlm.nih.gov/pubmed/37193698
http://dx.doi.org/10.1038/s41467-023-38443-3

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