Fragile X Messenger Ribonucleoprotein 1 (FMR1), a novel inhibitor of osteoblast/osteocyte differentiation, regulates bone formation, mass, and strength in young and aged male and female mice

Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene mutations lead to fragile X syndrome, cognitive disorders, and, in some individuals, scoliosis and craniofacial abnormalities. Four-month-old (mo) male mice with deletion of the FMR1 gene exhibit a mild increase in cortical and cancellous femoral b...

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Detalles Bibliográficos
Autores principales: Deosthale, Padmini, Balanta-Melo, Julián, Creecy, Amy, Liu, Chongshan, Marcial, Alejandro, Morales, Laura, Cridlin, Julita, Robertson, Sylvia, Okpara, Chiebuka, Sanchez, David J., Ayoubi, Mahdi, Lugo, Joaquín N., Hernandez, Christopher J., Wallace, Joseph M., Plotkin, Lilian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188597/
https://www.ncbi.nlm.nih.gov/pubmed/37193680
http://dx.doi.org/10.1038/s41413-023-00256-x

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