Hairy cell leukemia with isolated bone lesions

KEY CLINICAL MESSAGE: (18)F‐FDG PET/CT has clinical relevance in HCL at diagnosis and for the follow‐up of patients treated, especially in case of atypical presentations such as bone involvements (which are probably underestimated) and poor bone marrow infiltration. ABSTRACT: Bone lesions are rarely...

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Detalles Bibliográficos
Autores principales: Cailly, Laura, Gruchet, Cécile, Maitre, Elsa, Guidez, Stephanie, Delwail, Vincent, Systchenko, Thomas, Moya, Niels, Sabirou, Florence, Levy, Anthony, Bobin, Arthur, Gardeney, Hélène, Nsiala, Laly, Vonfeld, Mathilde, Chacon, Aurélia, Pichon, Aurélien, Bouyer, Sabrina, Baslé, Caroline, Dindinnaud, Elodie, Chomel, Jean‐Claude, Raimbault, Anna, Borde‐Mougenot, Florence, Troussard, Xavier, Tomowiak, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188895/
https://www.ncbi.nlm.nih.gov/pubmed/37207087
http://dx.doi.org/10.1002/ccr3.7343
Descripción
Sumario:KEY CLINICAL MESSAGE: (18)F‐FDG PET/CT has clinical relevance in HCL at diagnosis and for the follow‐up of patients treated, especially in case of atypical presentations such as bone involvements (which are probably underestimated) and poor bone marrow infiltration. ABSTRACT: Bone lesions are rarely reported in Hairy Cell Leukemia (HCL). We report two BRAF(V600E) mutated HCL patients presented bone lesions at foreground, poor bone marrow involvement, and the important role (18)F‐FDG PET/CT played in their management. We discuss the crucial role that (18)F‐FDG PET/CT could play in HCL routine practice.

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