Clinically practical pharmacometrics computer model to evaluate and personalize pharmacotherapy in pediatric rare diseases: application to Graves' disease

OBJECTIVES: Graves' disease (GD) with onset in childhood or adolescence is a rare disease (ORPHA:525731). Current pharmacotherapeutic approaches use antithyroid drugs, such as carbimazole, as monotherapy or in combination with thyroxine hormone substitutes, such as levothyroxine, as block-and-r...

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Detalles Bibliográficos
Autores principales: Steffens, Britta, Koch, Gilbert, Gächter, Pascal, Claude, Fabien, Gotta, Verena, Bachmann, Freya, Schropp, Johannes, Janner, Marco, l'Allemand, Dagmar, Konrad, Daniel, Welzel, Tatjana, Szinnai, Gabor, Pfister, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188966/
https://www.ncbi.nlm.nih.gov/pubmed/37206476
http://dx.doi.org/10.3389/fmed.2023.1099470

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