The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway

The pathogenic mechanisms of pancreatic cancer (PC) are still not fully understood. Ubiquitination modifications have a crucial role in tumorigenesis and progression. Yet, the role of MINDY2, a member of the motif interacting with Ub-containing novel DUB family (MINDY), as a newly identified deubiqu...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Liu, Songbai, Zhu, Changhao, Li, Yongning, Li, Ying, Fei, Xiaobin, Hou, Junyi, Wang, Xing, Pan, Yaozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189038/
https://www.ncbi.nlm.nih.gov/pubmed/37207150
http://dx.doi.org/10.3389/fonc.2023.1169833

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