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The adaptor protein TRAF3 is an immune checkpoint that inhibits myeloid-derived suppressor cell expansion

Myeloid-derived suppressor cells (MDSCs) are aberrantly expanded in cancer patients and under other pathological conditions. These cells orchestrate the immunosuppressive and inflammatory network to facilitate cancer metastasis and mediate patient resistance to therapies, and thus are recognized as...

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Detalles Bibliográficos
Autores principales: Zhu, Sining, Lalani, Almin I., Jin, Juan, Sant’Angelo, Derek, Covey, Lori R., Liu, Kebin, Young, Howard A., Ostrand-Rosenberg, Suzanne, Xie, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189059/
https://www.ncbi.nlm.nih.gov/pubmed/37207205
http://dx.doi.org/10.3389/fimmu.2023.1167924