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The adaptor protein TRAF3 is an immune checkpoint that inhibits myeloid-derived suppressor cell expansion
Myeloid-derived suppressor cells (MDSCs) are aberrantly expanded in cancer patients and under other pathological conditions. These cells orchestrate the immunosuppressive and inflammatory network to facilitate cancer metastasis and mediate patient resistance to therapies, and thus are recognized as...
Autores principales: | Zhu, Sining, Lalani, Almin I., Jin, Juan, Sant’Angelo, Derek, Covey, Lori R., Liu, Kebin, Young, Howard A., Ostrand-Rosenberg, Suzanne, Xie, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189059/ https://www.ncbi.nlm.nih.gov/pubmed/37207205 http://dx.doi.org/10.3389/fimmu.2023.1167924 |
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