Efficient ex vivo expansion of conserved element vaccine-specific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates

HIV-specific T cells are necessary for control of HIV-1 replication but are largely insufficient for viral clearance. This is due in part to these cells’ recognition of immunodominant but variable regions of the virus, which facilitates viral escape via mutations that do not incur viral fitness cost...

Descripción completa

Detalles Bibliográficos
Autores principales: Dross, Sandra, Venkataraman, Rasika, Patel, Shabnum, Huang, Meei-Li, Bollard, Catherine M., Rosati, Margherita, Pavlakis, George N., Felber, Barbara K., Bar, Katharine J., Shaw, George M., Jerome, Keith R., Mullins, James I., Kiem, Hans-Peter, Fuller, Deborah Heydenburg, Peterson, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189133/
https://www.ncbi.nlm.nih.gov/pubmed/37207227
http://dx.doi.org/10.3389/fimmu.2023.1188018

Ejemplares similares

Ejemplares similares