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FDXR drives primary and endocrine-resistant tumor cell growth in ER+ breast cancer via CPT1A-mediated fatty acid oxidation

BACKGROUND: The majority of breast cancers (BCs) expressing estrogen receptor (ER) have shown endocrine resistance. Our previous study demonstrated that ferredoxin reductase (FDXR) promoted mitochondrial function and ER+ breast tumorigenesis. But the underlying mechanism is not clear. METHODS: Liqui...

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Detalles Bibliográficos
Autores principales:	Yan, Chaojun, Gao, Ronghui, Gao, Chuan, Hong, Kai, Cheng, Meng, Liu, Xiaojing, Zhang, Qing, Zhang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189134/ https://www.ncbi.nlm.nih.gov/pubmed/37207154 http://dx.doi.org/10.3389/fonc.2023.1105117

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